This article is from Molecular Vision, volume 20.AbstractPurpose: Circadian rhythms are central to vision and retinal physiology. A circadian clock located within the retina controls various rhythmic processes including melatonin synthesis in photoreceptors. In the present study, we evaluated the rhythmic expression of clock genes and clock output genes in retinal explants maintained for several days in darkness. Methods: Retinas were dissected from Wistar rats, either wild-type or from the... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043612
byAbouzeid, Hana; Youssef, Mohamed A.; Bayoumi, Nader; ElShakankiri, Nihal; Marzouk, Iman; Hauser, Philippe; Schorderet, Daniel F.
This article is from Molecular Vision, volume 18.AbstractPurpose: To report the clinical and genetic study of two families of Egyptian origin with clinical anophthalmia. To further determine the role of the retina and anterior neural fold homeobox gene (RAX) in anophthalmia and associated cerebral malformations. Methods: Three patients with clinical anophthalmia and first-degree relatives from two consanguineous families of Egyptian origin underwent full ophthalmologic, general and neurologic... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380941
This article is from Molecular Vision, volume 20.AbstractPurpose: To report changes in the tapetal-like reflex in a female carrier of RPGR ORF15 c.3395delA X-linked retinitis pigmentosa (XLRP) between examinations at 16 and 22 years of age, and to report the observation that the tapetal-like reflex faded due to exposure to daylight and reappeared with prolonged dark adaptation at 22 years of age. Methods: Clinical examination, kinetic Goldmann perimetry, dark adaptometry, fundus... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063355